Ugandan media personality and entrepreneur Mami Deb, born Deborah Nantongo, is taking a bold new step in her career with the launch of her upcoming talk show, “Let’s Talk with Mami Deb.” Known for her candid personality and influence from reality television, the show marks a new chapter following her exit from Kampala Crème in 2025 to pursue fresh opportunities.

The new show builds on a concept she has already tested through her online conversations, where she gained popularity for engaging women on real life issues such as relationships, marriage, and personal growth.
Unlike traditional talk shows, “Let’s Talk with Mami Deb” promises to be a full entertainment experience. Viewers can expect a blend of laughter, honest and unfiltered conversations, a touch of drama, and live performances from popular artists, alongside surprise guest appearances. The format reflects Mami Deb’s signature style bold, relatable, and engaging.
At the heart of the show is a strong social impact mission. In every episode, Mami Deb will give UGX 1,000,000 to a deserving single mother, reinforcing her long-standing commitment to supporting women. Her generosity has been seen before, including moments where she has financially supported women to uplift their livelihoods.
Speaking during the unveiling, she emphasized the importance of community and collective support:
“If you know a woman who is doing her best and just needs a little support to feed and care for her children, please reach out to us. This is about showing up for each other.”
The show is expected to resonate strongly with audiences, particularly women navigating everyday challenges, by offering both entertainment and meaningful empowerment. With her growing influence and authentic voice, Mami Deb is positioning “Let’s Talk with Mami Deb” as more than just a show it’s a platform for conversation, connection, and real change.
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